The group has multiple synthesis projects as Prof. Waynant begins his independent career. Most of the project center on target driven glycosides and other biologically important natural products as well as ligand development for metal catalysts.
The group also focuses on new polymeric materials as well as the building of stimuli-responsive and stimuli-reactive polymeric surfaces as well as polymer brush derived sensors.
European Journal of Inorganic Chemistry
Nicolas A. Johnson, Samuel R. Wolfe, Human Kabir, Gabriel A. Andrade, Glenn P.A. Yap, Zachariah M. Heiden, James G. Moberly, Mark F. Roll, and Kristopher V. Waynant
Experimental and computational investigation of reactions involving the redox-active arylazothioformamide ligand with multiple Cu(I) sources is described. Cu(I) halides produce dimeric 1:1 coordination species, while non-coordinating counter ions (BF4 and PF6) gave 2:1 species. Computational comparisons of bond length and angles suggest that the Cu atom remains in the +1 oxidation state.
Journal of Chemical Education
Daniel E. Felton, Martina Ederer, Timothy Steffens, Patricia L. Hartzell and Kristopher V. Waynant
A simple assay to quantify glyphosate concentrations in environmental samples was developed as part of an interdisciplinary effort linking introductory laboratory courses in chemistry, biology, and microbiology. Regression analysis indicated that the assay is linear up to 20.0 ppm, making it particularly useful for detection of low levels of glyphosate in environmental samples. The assay can be used to quantify the activity of glyphosate-degrading soil microorganisms by comparing glyphosate levels between autoclaved and nonautoclaved soil slurries.
Kristopher V. Waynant, Hyung-Jun Koo, Chunjie Zhang and Paul V. Braun
Version of Record online: 6 JUL 2016 | DOI: 10.1002/pat.3861
Quaternary ammonium fluoride polymer brush thin-film surfaces synthesized from surface-initiated atom transfer radical polymerization and post-polymerization modification proved capable of degrading the known pesticide coumaphos. Coumaphos degradation was visualized through detection of known fluorescent by-product chlorferon. Brush surfaces allow for various pesticide delivery methods and could prove useful for detection and degradation of pesticides and chemical threats.
Synthesis of β-C-GlcNAc Ser from β-C-Glc Ser